Summary of Functional Type.
Summary of Interaction.
Interaction graph
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Official
Symbol |
type |
pmid |
method |
Sample
Type |
Region |
Sample
Number
GC |
Sample
Number
nonGC |
Normal
vs.
GC |
Early-stage
vs.
advanced-stage |
Hpylori |
Result |
Functional
Type |
Overall
Survival |
Disease-free
Survival |
AUC |
| FZD7 |
protein-coding |
29559846 |
IHC |
tissue |
China |
251 |
60 |
Up |
- |
Not Related |
FZD7 was overexpressed in clinical GC samples, and thus was correlated with tumor invasion, lymphatic and organ metastasis, late TNM stages and poor patient survival. Furthermore, RNA interference-mediated . Moreover, ablation of FZD7 down-regulated EMT and the expression levels of cancer stem cell markers, and these inhibitions were associated with attenuated canonical Wnt/β-catenin signaling |
target/prognosis |
< 0.001 |
< 0.001 |
- |
| MIR1275 |
miRNA |
31357957 |
qRT-PCR |
tissue |
China |
120 |
120 |
Down |
- |
Not Related |
The expression of miR-1275 was reduced in GC tissues. We validated in 120 GC patients specimens that low miR-1275 expression levels were closely associated with lymph node metastasis, Borrmann type and poor prognosis. |
prognosis |
< 0.001 |
- |
- |
| MIR204 |
miRNA |
29386218 |
CDX |
tissue |
|
50gc, 50 non-gc |
|
- |
- |
Not Related |
LINC01234 expression was significantly upregulated in gastric cancer tissues and was associated with larger tumor size, advanced TNM stage, lymph node metastasis, and shorter survival time. Furthermore, knockdown of LINC01234-induced apoptosis and growth arrest in vitro and inhibited tumorigenesis in mouse xenografts. |
mechanism |
- |
- |
- |
