Summary of Functional Type.
Summary of Interaction.
Interaction graph
The select node information.
Browse for
Official Symbol |
type |
pmid |
method |
Sample Type |
Region |
Sample Number GC |
Sample Number nonGC |
Normal vs. GC |
Early-stage vs. advanced-stage |
Hpylori |
Result |
Functional Type |
Overall Survival |
Disease-free Survival |
AUC |
MIR107 |
miRNA |
26406411 |
qRT-PCR |
tissue |
Iran |
36 |
36 |
Up |
- |
|
Quantitative RT-PCR analysis on total RNA demonstrated significant overexpression of miR-107 in 36 GC tumor samples, in comparison to the its adjacent normal tissue of the same patients (p = 0.04) |
target |
- |
- |
- |
MIR191 |
miRNA |
24603541 |
qRT-PCR |
cell line |
China |
- |
- |
Up |
- |
|
Examination of miR-191 and miR-425 expression in four GC cell lines (HGC-27,MGC-803, MKN-45 and SGC-7901) indicated an obvious upregulation of miR-191/425 in HGC-27, MGC-803, and SGC-7901 cell lines when compared to adjacent non-tumor tissues and five normal gastric tissues from healthy people |
mechanism |
- |
- |
- |
MIR222 |
miRNA |
22432036 |
qRT-PCR |
serum |
- |
82 |
82 |
UP |
- |
|
miR-222 demonstrated significantly elevated levels in GC group with more than 2-fold change(P<0.05) |
target |
- |
- |
0.65 |
MIR222 |
miRNA |
25129310 |
qRT-PCR |
plasma |
China |
114 |
56 |
UP |
- |
|
In this study, our results demonstrated that the levels of circulating miR-222 in patients with GC were significantly increased, compared with CAG and healthy controls. In addition, higher level of circulating miR-222 had also been found in the plasma of CAG patients compared with healthy controls, indicating the dysregulated expression of miR-222 might be involved in the early events of GC malignancy. |
target;prognosis |
22.428 % |
25.267% |
0.85 |
MIR107 |
miRNA |
26406411 |
qRT-PCR |
serum |
Iran |
36 |
36 |
Up |
- |
|
significant elevated levels of miR-107 in serum of GC patients compared to controls |
diagnosis |
- |
- |
0.63 |
MIR191 |
miRNA |
24603541 |
qRT-PCR |
tissue |
China |
75 |
75 |
Up |
Up |
|
The miR-191 Cluster Is Highly Expressed in Gastric Cancer (GC) |
target |
- |
- |
- |
MIR17 |
miRNA |
20234369 |
qRT-PCR |
plasma |
Japan |
69 |
30 |
Up |
- |
|
miR-17-5p were significantly higher in GC patients than in controls (P = 0.006) |
target |
- |
- |
- |
MIR191 |
miRNA |
24603541 |
qRT-PCR |
serum |
China |
57 |
58 |
Up |
Up |
|
when using miR-16 as an endogenous control, the relative level of miR-191 in GC serum was significantly higher than those in the controls (p < 0.01) |
target,diagnosis |
- |
- |
0.85 |