Browse for blood
Official
Symbol |
type |
pmid |
method |
Sample
Type |
Region |
Sample
Number
GC |
Sample
Number
nonGC |
Normal
vs.
GC |
Early-stage
vs.
advanced-stage |
Hpylori |
Result |
Functional
Type |
Overall
Survival |
Disease-free
Survival |
AUC |
| ABCB1 |
protein-coding |
23801278 |
CRS-PCR |
blood |
China |
365 |
367 |
- |
- |
No Reports |
The allele and genotype frequencies of c.159G > T and c.1564A > T were statistically different between gastric cancer patients and cancer-free controls. |
diagnosis |
- |
- |
- |
| APBA2 |
protein-coding |
24385013 |
RT-MSP |
PPLF/blood |
China |
92 |
- |
- |
- |
No Reports |
The frequency of MINT2 methylation in pairing PPLF and blood samples from 92 GC patients was 40.2% (37/92) and 39.1% (36/92), respectively. Methylated MINT2 in tumor tissues, pairing PPLF, and blood samples were very approximate. Aberrant MINT2 methylation in tumor tissues and pairing PPLF or blood samples were closely related to peritoneal dissemination, tumor progression, and poor prognosis. |
diagnosis/prognosis |
- |
< 0.0001 |
0.710/0.696 |
| CD14 |
protein-coding |
17438094 |
Reporter gene assays; PCR-RFLP methods |
blood |
China |
470 |
470 |
- |
- |
Related |
Two SNPs (-651C>T and -260C>T) were identified, of which the -260CT and -260TT genotypes were associated with elevated risk of gastric carcinoma (OR, 1.77; 95% CI, 1.09-2.85 and OR, 1.95; 95% CI, 1.20-3.16, respectively). Haplotype analysis suggested a synergistic effect of the two SNPs (OR for the T(-651)-T(-260) haplotype, 3.39 versus OR for the C(-651)-T(-260) haplotype, 1.45; P = 0.02), which is consistent with reporter gene assays. A multiplicative joint effect between H. pylori infection and -260C>T polymorphism was observed (OR for the presence of both -260TT genotype and H. pylori infection, 4.03; 95% CI, 1.80-9.04). Patients had significantly higher sCD14 than controls (1,866 +/- 2,535 ng/mL versus 1,343 +/- 2,119 ng/mL; P < 0.001), and this difference was associated with the CD14 -260 polymorphism and H. pylori infection. |
- |
- |
- |
- |
| MIR494 |
miRNA |
29568970 |
qRT-PCR |
blood |
China |
50 |
50 |
Down |
- |
No Reports |
The expression level of miR-494 was lower in patients with GC than in healthy control subjects. The expression of miR-494 and BAG-1 exhibited opposing trends of in cinobufacini-treated cells, with miR-494 was upregulated and BAG-1 downregulated by cinobufacini. The miR-494 inhibitor partially reversed the cinobufacini-induced decreased expression of BAG-1. |
mechanism |
- |
- |
- |
Summary of Functional Type.
Summary of Interaction.
Interaction graph
The select node information.
