Browse for snoRNA
Official Symbol |
type |
pmid |
method |
Sample Type |
Region |
Sample Number GC |
Sample Number nonGC |
Normal vs. GC |
Early-stage vs. advanced-stage |
Hpylori |
Result |
Functional Type |
Overall Survival |
Disease-free Survival |
AUC |
SNORD105B |
snoRNA |
29554660 |
qRT-PCR |
tissue |
China |
109 |
109 |
Up |
- |
No Reports |
The snord105b was upregulated in GC tissues and associated with tumor size, differentiation, and pathological stage in GC. |
target |
- |
- |
- |
SNORD105B |
snoRNA |
29554660 |
qRT-PCR |
serum |
China |
68 |
25 |
Up |
- |
No Reports |
The snord105b was upregulated in GC serum samples when compared with healthy donors. |
target |
- |
- |
- |
SNORD105B |
snoRNA |
29554660 |
Cell proliferation assay; Invasion and migration assay; Clonogenic assay |
cell line |
- |
- |
- |
- |
- |
No Reports |
Snord105b promotes the proliferation, migration,invasion and clonogenictiy in multiple GC cell lines. The oncoqenic activity of snord105b was also confirmed with in vivo data. Mechanistically, snord105b specifically bound to ALDOA and affected C-myc, which plays a key role in carcinogenesis and tumor development. |
target |
- |
- |
- |
SNORD105B |
snoRNA |
29554660 |
RIP assay; CHIRP-MS |
cell line |
- |
- |
- |
- |
- |
No Reports |
Snord105b is associated with the ALDOA protein |
target |
- |
- |
- |
SNORD105B |
snoRNA |
29554660 |
Xenograft mice models |
mice |
- |
- |
- |
- |
- |
No Reports |
Promotes the growth of transplanted tumors in vivo. |
target |
- |
- |
- |
Summary of Functional Type.
Summary of Interaction.
Interaction graph
The select node information.