| Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
| tissue |
30 |
30 |
qRT-PCR |
China |
No Reports |
Up |
- |
- |
LINC00483 level was increased in gastric cancer tissues and cells. . Besides, inhibition of LINC00483 decreased xenograft tumor growth by regulating miR-490-3p/MAPK1 axis. |
32293550 |
| cell line |
- |
- |
Cell viability assay; Invasion and migration assay; Flow cytometry |
- |
No Reports |
- |
- |
Knockdown of LINC00483 inhibited cells viability, migration and invasion but promoted apoptosis in gastric cancer cells. |
Knockdown of LINC00483 inhibited cells viability, migration and invasion but promoted apoptosis in gastric cancer cells. |
32293550 |
| cell line |
- |
- |
Luciferase reporter assay |
- |
No Reports |
- |
- |
- |
LINC00483 could increase MAPK1 expression by competitively sponging miR-490-3p. miR-490-3p overexpression suppressed gastric cancer development, which was abated by introduction of LINC00483 |
32293550 |
| mice |
- |
- |
Xenograft mice models |
- |
No Reports |
- |
- |
- |
Knockdown of LINC00483 decreases tumor growth in gastric cancer xenograft model. |
32293550 |
