MKGC: a curated molecular knowledgebase for gastric cancer


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Gene Summary for ATF7 Gene

Official Symbol ATF7 Gene Type protein-coding
Full Name activating transcription factor 7 Entrez 11016
Ensembl ID ENSG00000170653 HGNC 792
Aliases ATFA Chromosome Location Chromosome 12, NC_000012.12 (53507856..53626382, complement)
Expression Ubiquitous expression in lung (RPKM 9.8), fat (RPKM 9.2) and 25 other tissues
Summary -

Paper for ATF7 Gene

PMID Author Year ID in Paper
 Conclusion
29754469 Xiaoyi Hu 2018 ATF7 miR-103a-3p promotes the proliferation of GC cell by targeting and suppressing ATF7 in vitro

Experiment for ATF7 Gene

Sample Type Sample Number GC Sample Number nonGC Method Region Hpylori Normal vs. GC Early-stage vs. Advanced stage Biological Functions in GC Cells Result PMID
cell line - - Cell proliferation assay; Cell colony formation assay; Flow cytometry - No Reports - - ATF7 overexpression eliminated the effects of miR-103a-3p siATF7 increased the accumulation of cells at the G2/M phase; ATF7 rescues the cellular phenotypes induced by miR-103a-3p in gastric cancer cells. 29754469
cell line - - Western blot - No Reports - - - both miR-103a-3p overexpression and ATF7 silencing promoted the expression of CDK2 29754469
cell line - - Luciferase reporter assay - No Reports - - - miR-103a-3p directly regulates ATF7 expression in GC cells. 29754469

Function for ATF7 Gene

Functional Type AUC Overall Survival Disease-free Survival

Interaction for ATF7 Gene

Interaction Gene Method PMID
miR-103a-3p Luciferase reporter assay 29754469
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