MKGC: a curated molecular knowledgebase for gastric cancer


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Gene Summary for CACUL1 Gene

Official Symbol CACUL1 Gene Type protein-coding
Full Name CDK2 associated cullin domain 1 Entrez 143384
Ensembl ID ENSG00000151893 HGNC 23727
Aliases C10orf46, CAC1 Chromosome Location Chromosome 10, NC_000010.11 (118676411..118754970, complement)
Expression Ubiquitous expression in testis (RPKM 11.0), bone marrow (RPKM 9.1) and 25 other tissues
Summary -

Paper for CACUL1 Gene

PMID Author Year ID in Paper
Conclusion
24004834 Ying Kong 2013 CACUL1 CACUL1 is a potential therapeutic target for the treatment of aggressive gastric cancer

Experiment for CACUL1 Gene

Sample Type Sample Number GC Sample Number nonGC Method Region Hpylori Normal vs. GC Early-stage vs. Advanced stage Biological Functions in GC Cells Result PMID
tissue 43 43 qRT-PCR; IHC China Related Up Up - CACUL1 was highly expressed in gastric cancer tissues and negatively correlated with gastric cancer differentiation and TNM stage. In addition, CACUL1 expression was high in H.pylori-infected tissues compared with H.pylori non-infected tissue. 24004834

Function for CACUL1 Gene

Functional Type AUC Overall Survival Disease-free Survival
target - - -

Interaction for CACUL1 Gene

Interaction Gene Method PMID
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