Gene Summary for DUSP5P1 Gene
| Official Symbol |
DUSP5P1 |
Gene Type |
lncRNA |
| Full Name |
dual specificity phosphatase 5 pseudogene 1 |
Entrez |
574029
|
| Ensembl ID |
- |
HGNC |
32020
|
| Aliases |
DUSP5P
|
Chromosome Location |
Chromosome 1, NC_000001.11 (228644910..228652412)
|
| Expression |
Low expression observed in reference dataset
|
| Summary |
-
|
Paper for DUSP5P1 Gene
| PMID |
Author |
Year |
ID in Paper
|
Conclusion |
| 30733230 |
Xiaohong Wang |
2019 |
DUSP5P1 |
C8orf76 directly binds to oncogenic lncRNA DUSP5P1 to induce its expression and activates MAPK signaling. C8orf76 plays a pivotal oncogenic role in gastric carcinogenesis and is an independent prognostic factor for gastric cancer patients. |
Experiment for DUSP5P1 Gene
| Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
| cell line |
- |
- |
Luciferase reporter assay; Western blot; qRT-PCR; ChIP-PCR |
- |
No Reports |
- |
- |
- |
DUSP5P1 is a direct downstream target of C8orf76 |
30733230 |
| cell line |
- |
- |
Cell proliferation assay; Cell colony formation assay; Invasion and migration assays; Flow cytometry |
- |
No Reports |
- |
- |
- |
DUSP5P1 promotes gastric cancer cell growth in vitro. |
30733230 |
| mice |
- |
- |
Xenograft mice models |
- |
No Reports |
- |
- |
- |
Significantly more proliferating cells and fewer apopto- tic cells were shown in DUSP5P1-transfected xenografts as compared with control group by Ki-67 and TUNEL assays. |
30733230 |
Function for DUSP5P1 Gene
| Functional Type |
AUC |
Overall Survival |
Disease-free Survival |
| mechanism |
- |
- |
- |
Interaction for DUSP5P1 Gene
| Interaction Gene |
Method |
PMID |
