MKGC: a curated molecular knowledgebase for gastric cancer


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Gene Summary for FLJ22763 Gene

Official Symbol FLJ22763 Gene Type lncRNA
Full Name chromosome 3 open reading frame 85 Entrez https://www.ncbi.nlm.nih.gov/nuccore/10439276
Ensembl ID - HGNC -
Aliases Chromosome Location Chromosome 3, NC_000003.12 (109136719..109151401)
Expression -
Summary -

Paper for FLJ22763 Gene

PMID Author Year ID in Paper
 Conclusion
30716442 Gang Zhang 2019 FLJ22763 FLJ22763 may act as a suppressor gene to regulate the expression of ACLY, and its down-expression may be an independent prognostic factor in patients with GC.

Experiment for FLJ22763 Gene

Sample Type Sample Number GC Sample Number nonGC Method Region Hpylori Normal vs. GC Early-stage vs. Advanced stage Biological Functions in GC Cells Result PMID
tissue 5 5 qRT-PCR China No Reports Down - - FLJ22763, a novel lncRNA, had significantly lower expression in GC tissues. 30716442
tissue 303 - qRT-PCR China No Reports - Down - Decreased expression of FLJ22763 was positively correlated with a lower-level histological grade and the depth of invasion. Patients with high FLJ22763 expression levels had a higher five-year survival rate. 30716442
cell line - - Cell proliferation assay; Invasion and migration assays - No Reports - - LncRNA FLJ22763 inhibits cells proliferation, migration, and invasion LncRNA FLJ22763 inhibits cells proliferation, migration, and invasion 30716442
mice - - Xenograft mice models - No Reports - - - LncRNA FLJ22763 inhibits tumorigenesis of GC cells in vivo 30716442
cell line - - qRT-PCR; Cell tranfection; Western blot - No Reports - - - FLJ22763 was negatively associated with ACLY, regulating the mRNA and protein levels of ACLY 30716442

Function for FLJ22763 Gene

Functional Type AUC Overall Survival Disease-free Survival
target/prognosis - 0.003 -

Interaction for FLJ22763 Gene

Interaction Gene Method PMID
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