Search Result
Gene Summary for FOXM1 Gene
| Official Symbol |
FOXM1 |
Gene Type |
protein-coding |
| Full Name |
forkhead box M1 |
Entrez |
2305
|
| Ensembl ID |
ENSG00000111206 |
HGNC |
3818
|
| Aliases |
FKHL16A, FOXM1B, FOXM1C, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TRIDENT, FOXM1
|
Chromosome Location |
Chromosome 12, NC_000012.12 (2857680..2877174, complement)
|
| Expression |
Broad expression in testis (RPKM 16.1), bone marrow (RPKM 11.2) and 16 other tissues
|
| Summary |
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
|
Paper for FOXM1 Gene
| PMID |
Author |
Year |
ID in Paper
|
Conclusion |
| 27086911 |
Yangyang Wang |
2016 |
FoxM1 |
These results thus reveal the crucial role played by miR-320a in limiting gastric carcinoma by directly targeting FoxM1- P27KIP1 axis. |
Experiment for FOXM1 Gene
| Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
| tissue |
14 |
14 |
qRT-PCR |
China |
No Reports |
Up |
- |
- |
miR-320a expression correlates inversely with expression of FoxM1, a key cell cycle regulator involved in gastric carcinoma. FOXM1 expression was increased in GC tissues. |
27086911 |
| cell line |
- |
- |
Luciferase reporter assay |
- |
No Reports |
- |
- |
- |
FoxM1 is a direct target of miR-320a |
27086911 |
Function for FOXM1 Gene
| Functional Type |
AUC |
Overall Survival |
Disease-free Survival |
| mechanism |
- |
- |
- |
Interaction for FOXM1 Gene
| Interaction Gene |
Method |
PMID |
|
miR-320a |
Luciferase reporter assay |
27086911
|
|
