Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
cell line |
- |
- |
Phase-contrast microscopy |
- |
No Reports |
- |
- |
- |
JMJD2B inhibition induces the epithelial morphology of gastric cancer cells |
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cell line |
- |
- |
qRT-PCR; Western blot |
- |
No Reports |
- |
- |
- |
JMJD2B repression results in downregulation of mesenchymal markers and upregulation of epithelial markers |
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cell line |
- |
- |
Luciferase reporter activity assay; ChIP assay; |
- |
No Reports |
- |
- |
- |
JMJD2B is physically associated with b-catenin to regulate vimentin promoter. |
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cell line |
- |
- |
Cell invasion and migration assay |
- |
No Reports |
- |
- |
JMJD2B inhibition results in diminished invasion and metastasis in vitro |
JMJD2B inhibition results in diminished invasion and metastasis in vitro |
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mice |
- |
- |
Xenograft mice models |
- |
No Reports |
- |
- |
- |
JMJD2B knockdown inhibits tumor metastasis in vivo. |
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tissue |
101 |
- |
IHC |
China |
No Reports |
- |
- |
- |
JMJD2B expression was positively correlated with tumor size, differen_x005ftiation status, invasion, lymph node status, distant metastasis, and TNM stage of patients with gastric cancer |
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