| Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
| tissue |
84 |
29 |
qRT-PCR |
China |
No Reports |
Down |
- |
- |
KRT19P3 expression was significantly decreased in gastric cancer tissues. Lower expression of KRT19P3 was found to be associated with lager tumor size (≥ 5 cm), advanced TNM stage, Lauren's classification, and positive LNM. Patients with lower KRT19P3 expression had worse overall survival (OS) and disease-free sur_x005fvival (DFS) compared with those patients with higher KRT19P3 expression Univariate analysis demonstrated that patients with lower KRT19P3 expression tended to have a higher risk of death. |
31409899 |
| cell line |
- |
- |
Cell proliferation assay; Cell invasion and migration assays; |
- |
No Reports |
- |
- |
KRT19P3 inhibited GC cell proliferation and induced apoptosis, suppressed GC cell migration and invasion in vitro. |
KRT19P3 inhibited GC cell proliferation and induced apoptosis, suppressed GC cell migration and invasion in vitro. |
31409899 |
| mice |
- |
- |
Xenograft mice models |
- |
No Reports |
- |
- |
- |
KRT19P3 suppressed GC cell migration and invasion and tumor growth in vivo. |
31409899 |
| cell line |
- |
- |
RNA pull-down assay; RIP; Western blot |
- |
No Reports |
- |
- |
- |
KRT19P3 could bind COPS7A directly and might regulate COPS7A activity in GC |
31409899 |
