Search Result
Gene Summary for LINC02859 Gene
| Official Symbol |
LINC02859 |
Gene Type |
lncRNA |
| Full Name |
long intergenic non-protein coding RNA 2859 |
Entrez |
101928316
|
| Ensembl ID |
- |
HGNC |
54399
|
| Aliases |
|
Chromosome Location |
Chromosome 11, NC_000011.10 (30684638..30735059, complement)
|
| Expression |
Biased expression in salivary gland (RPKM 2.0) and kidney (RPKM 0.3)
|
| Summary |
-
|
Paper for LINC02859 Gene
| PMID |
Author |
Year |
ID in Paper
|
Conclusion |
| 31207155 |
Chengyun Li |
2019 |
LncRNA-LOC101928316 |
Collectively, our data provided the key role of LOC101928316 in the tumorigenesis of GC. In addition, the present study elucidates LOC101928316 potential regulatory network, which may help us to lead a better knowing of the pathogenesis of GC and probe the lncRNA as a novel biomarker to diagnosis and therapy for this malignant tumor. |
Experiment for LINC02859 Gene
| Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
| tissue |
90 |
90 |
qRT-PCR |
China |
No Reports |
Down |
- |
- |
LOC101928316 was significantly downregulated in gastric cancer (GC) tissues specimen, GC cell lines, and associated with the GC patients tumor, node, and metastasis (TNM) stage and degree of differentiation. |
31207155 |
| cell line |
- |
- |
Cell proliferation assay; Invasion and migration assay; Flow cytometry |
- |
No Reports |
- |
- |
LOC101928316 overexpression can significantly inhibit GC cell migration, invasion, and proliferation. |
LOC101928316 overexpression can significantly inhibit GC cell migration, invasion, and proliferation. |
31207155 |
| mice |
- |
- |
Xenograft mouse models |
- |
No Reports |
- |
- |
- |
LOC101928316 Overexpression inhibited gastric cancer cells tumorigenesis in vivo |
31207155 |
| cell line |
- |
- |
Western blot |
- |
No Reports |
- |
- |
- |
lenti-LOC101928316-Overexpression stable infected can remarkably inhibit the expression level of PI3K, p-AKT, mTOR, and p-mTOR in GC cells |
31207155 |
Function for LINC02859 Gene
| Functional Type |
AUC |
Overall Survival |
Disease-free Survival |
| target |
- |
- |
- |
Interaction for LINC02859 Gene
| Interaction Gene |
Method |
PMID |
|
