MKGC: a curated molecular knowledgebase for gastric cancer


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Gene Summary for PCAT18 Gene

Official Symbol PCAT18 Gene Type lncRNA
Full Name prostate cancer associated transcript 18 Entrez 728606
Ensembl ID ENSG00000265369 HGNC 49211
Aliases LINC01092 Chromosome Location Chromosome 18, NC_000018.10 (26687621..26703638, complement)
Expression Biased expression in prostate (RPKM 2.5), stomach (RPKM 1.5) and 4 other tissues
Summary -

Paper for PCAT18 Gene

PMID Author Year ID in Paper
 Conclusion
32119960 Xiao-Zhan Zhang 2020 PCAT18 Over-expressed lncRNA PCAT18 inhibits proliferation, migration and invasion of gastric cancer cells through regulation of miR-135b/CLDN11

Experiment for PCAT18 Gene

Sample Type Sample Number GC Sample Number nonGC Method Region Hpylori Normal vs. GC Early-stage vs. Advanced stage Biological Functions in GC Cells Result PMID
cell line - - Cell proliferation assay; Cell invasion and migration assays; Cell colony forming assay; - No Reports - - PCAT18 down-expression promoted proliferation, migration and invasion of gastric cancer cells. PCAT18 down-expression promoted proliferation, migration and invasion of gastric cancer cells. 32119960
mice - - Xenograft mice models - No Reports - - - In in-vivo experiment, PCAT18 over-expression restrained tumor growth and metastasis. 32119960
cell line - - Luciferase reporter assay; RIP - No Reports - - - PCAT18 is the direct target of miR-135b 32119960

Function for PCAT18 Gene

Functional Type AUC Overall Survival Disease-free Survival
target - - -

Interaction for PCAT18 Gene

Interaction Gene Method PMID
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