Search Result
Gene Summary for SNHG7 Gene
| Official Symbol |
SNHG7 |
Gene Type |
lncRNA |
| Full Name |
small nucleolar RNA host gene 7 |
Entrez |
84973
|
| Ensembl ID |
ENSG00000233016 |
HGNC |
28254
|
| Aliases |
NCRNA00061
|
Chromosome Location |
Chromosome 9, NC_000009.12 (136724594..136728184, complement)
|
| Expression |
Ubiquitous expression in ovary (RPKM 15.1), thyroid (RPKM 12.1) and 25 other tissues
|
| Summary |
-
|
Paper for SNHG7 Gene
| PMID |
Author |
Year |
ID in Paper
|
Conclusion |
| 29131253 |
M-W Wang |
2017 |
SNHG7 |
Relative expression of SNHG7 is upregulated in gastric cancer tissues and cells, and partially contributes to the development and progression of gastric cancer through regulation of p15 and p16 expressions. Thus, interference on expression of SNHG7 can provide critical the theoretical basis for inverting the malignant phenotype of gastric cancer in clinical practice. |
Experiment for SNHG7 Gene
| Sample Type |
Sample Number GC |
Sample Number nonGC |
Method |
Region |
Hpylori |
Normal vs. GC |
Early-stage vs. Advanced stage |
Biological Functions in GC Cells |
Result |
PMID |
| tissue |
68 |
68 |
qRT-PCR |
China |
No Reports |
Up |
- |
- |
The qRT-PCR experiment showed that in a total of 68 cases of cancer tissues and tumor-adjacent tissues, the relative expression of SNHG7 was upregulated in 48 cases of gastric cancer tissues and 5 gastric cancer cell lines. |
29131253 |
| cell line |
- |
- |
Cell proliferation assay; Flow cytometry |
- |
No Reports |
- |
- |
The in vitro experiments showed that after SNHG7 expression was interfered, the proliferation of gastric cancer cells was inhibited with an increase in apoptotic rate and arrest of cell cycle in G1/G0 phase. |
The in vitro experiments showed that after SNHG7 expression was interfered, the proliferation of gastric cancer cells was inhibited with an increase in apoptotic rate and arrest of cell cycle in G1/G0 phase. |
29131253 |
| mice |
- |
- |
Xenograft mice models |
- |
No Reports |
- |
- |
- |
Experiment on nude-mouse transplanted tumor model confirmed that after SNHG7 expression was interfered, in vivo tumor growth was inhibited. |
29131253 |
Function for SNHG7 Gene
| Functional Type |
AUC |
Overall Survival |
Disease-free Survival |
| target |
- |
- |
- |
Interaction for SNHG7 Gene
| Interaction Gene |
Method |
PMID |
|
