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Gene Summary for SNORD105B Gene

Official Symbol SNORD105B Gene Type snoRNA
Full Name small nucleolar RNA, C/D box 105B Entrez 100113382
Ensembl ID ENSG00000238531 HGNC 33572
Aliases Chromosome Location Chromosome 19, NC_000019.10 (10109749..10109840)
Expression -
Summary -

Paper for SNORD105B Gene

PMID Author Year ID in Paper
 Conclusion
29554660 Cong Zhang 2018 C/D-Box Snord105b Snord105b appears to be a novel oncogene and is clinically and functionally involved in the development of GC. Targeting snord105b and its pathway may provide new biomarkers or potential treatments for patients with GC.

Experiment for SNORD105B Gene

Sample Type Sample Number GC Sample Number nonGC Method Region Hpylori Normal vs. GC Early-stage vs. Advanced stage Biological Functions in GC Cells Result PMID
tissue 109 109 qRT-PCR China No Reports Up - - The snord105b was upregulated in GC tissues and associated with tumor size, differentiation, and pathological stage in GC. 29554660
serum 68 25 qRT-PCR China No Reports Up - - The snord105b was upregulated in GC serum samples when compared with healthy donors. 29554660
cell line - - Cell proliferation assay; Invasion and migration assay; Clonogenic assay - No Reports - - Snord105b promotes the proliferation, migration,invasion and clonogenictiy in multiple GC cell lines. The oncoqenic activity of snord105b was also confirmed with in vivo data. Mechanistically, snord105b specifically bound to ALDOA and affected C-myc, which plays a key role in carcinogenesis and tumor development. Snord105b promotes the proliferation, migration,invasion and clonogenictiy in multiple GC cell lines. The oncoqenic activity of snord105b was also confirmed with in vivo data. Mechanistically, snord105b specifically bound to ALDOA and affected C-myc, which plays a key role in carcinogenesis and tumor development. 29554660
cell line - - RIP assay; CHIRP-MS - No Reports - - - Snord105b is associated with the ALDOA protein 29554660
mice - - Xenograft mice models - No Reports - - - Promotes the growth of transplanted tumors in vivo. 29554660

Function for SNORD105B Gene

Functional Type AUC Overall Survival Disease-free Survival
target - - -

Interaction for SNORD105B Gene

Interaction Gene Method PMID
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